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14 | 9 | Read more | The role of mitochondrial dysfunctions due to oxidative and nitrosative stress in the chronic pain or chronic fatigue syndromes and fibromyalgia patients: peripheral and central mechanisms as therapeutic targets? | Vulnerability to Chronic Pain: Chronic pain often has more to do with general biological vulnerabilities than specific tissue problems | 12 | PainSci #52758. ❐ | I have a lot of tragic personal experience | Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis. | PubMed #24952854. ❐ | Autoimmune diseases | Trigger Points & Myofascial Pain Syndrome | Jia et al. | 35 | Why Does Pain Hurt? How an evolutionary wrong turn led to a biological glitch that condemned the animal kingdom — you included — to much louder, longer pain | 39 | headaches | Chronic subtle inflammation and “inflammaging” | Statin Therapy | PainScience.com | Vitamin D deficiency: a worldwide problem with health consequences. | PubMed #21412369. ❐ | O’Sullivan | Cramps, Spasms, Tremors & Twitches: The biology and treatment of unwanted muscle contractions | PubMed #20947763. ❐ | Adverse events associated with unblinded, but not with blinded, statin therapy in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid-Lowering Arm (ASCOT-LLA): a randomised double-blind placebo-controlled trial and its non-randomised non-blind extension phase. | spinal cord impingement | Does Fascia Matter? A detailed critical analysis of the clinical relevance of fascia science and fascia properties | 27 | PubMed #26223627. ❐ | 37 | alerted health care professionals and consumers | dysautonomia | Fibromyalgia and Positional Cervical Cord Compression Differ Only By Autonomic Nervous System Consequences: A Double-Blinded, Prospective Study. | On muscle, tendon and high heels. | sensitization | The pain of stuckness | PAINS | PubMed #31177555. ❐ | Psychological stress in early life as a predisposing factor for the development of chronic pain: Clinical and preclinical evidence and neurobiological mechanisms. | Sensitization in Chronic Pain: Pain itself can change how pain works, resulting in more pain with less provocation | updated | Unexplained neuropathy (especially channelopathy) | Complex regional pain syndrome (CRPS) | Facebook | PubMed #26316810. ❐ | Hou | Stupid, stupid neutrophils | All in your head: pure psychosomatic pain | 31 | Association between musculoskeletal pain with social isolation and loneliness: analysis of the English Longitudinal Study of Ageing. | A comprehensive review of opioid-induced hyperalgesia. | RSS | PainSci #52332. ❐ | PubMed #31194737. ❐ | PubMed #20639419. ❐ | more about fibromyalgia | Marshall and Warren got a Nobel prize in 2005 (acceptance speech) | Read more … | Non-obvious nerve entrapment | BACK TO TEXT | An evolutionary stress-response hypothesis for chronic widespread pain (fibromyalgia syndrome). | Epsom salts | Psychological amplification | PS Insomnia Until it Hurts | 2017 EDS International Classification | trigger points book | psychosomatic pain | PubMed #17224570. ❐ | Spatial summation | SITEMAP | PS Why Does Pain Hurt? | Comparison of spatial summation properties at different body sites. | 25 | PubMed #27402412. ❐ | Why Zebras Don’t Get Ulcers. | Claudication: the pain of impaired blood flow | PubMed #31019689. ❐ | It's All in Your Head | PubMed #23834645. ❐ | Loneliness & social isolation | inflammaging | Why all migraine patients should be treated with magnesium. | A functional substitution in the L-aromatic amino acid decarboxylase enzyme worsens somatic symptoms via a serotonergic pathway. | 26 | PainSci #52248. ❐ | Analgesic rebound | Neuroinflammation | Chronic pain does not work like acute pain | delayed-onset muscle soreness | Ehlers-Danlos syndrome hypermobility type is associated with rheumatic diseases. | 30 | Nutritional deficiencies: vitamin D and magnesium | PubMed #28760092. ❐ | NEW | PS The 3 Basic Types of Pain | PubMed #24578711. ❐ | The wilderness of the medically unexplained | Sensitization (somatic and visceral) | Syphilis | What’s New? | most Internet pages waste pixels on | systems perspective | PS A Rational Guide to Fibromyalgia | 7 | 32 | do a Google search for it to get around the paywall. | CONTACT | Ehlers–Danlos syndrome | Twitter | Channelopathies. | headache tutorial | 15 | Basic Self-Massage Tips for Myofascial Trigger Points | PainSci #52327. ❐ | PubMed #31209025. ❐ | Pain and the neuromatrix in the brain. | interview with Eliot A. Brinton | PainSci #53026. ❐ | iliopsoas muscle | Hagen | Side effects, especially statins, bisphosphonates, fluoroquinolones, retinoids | Facioscapulohumeral Muscular Dystrophy (FSHD) | PainSci #52620. ❐ | Guo et al. | Referred pain | PS Nerve Pain Is Overdiagnosed | HOME | lost it up there and then forgot it for almost twenty years | Elisa Arnaudo | ABOUT | chronic immune activation after infection | 20 | 3 | channelopathy | 13 | soreness after exercise | tension headaches | Multiple sclerosis | Paul Ingraham | Poisoned by Massage | bisphosphonate (Wikipedia) | PubMed #18400738. ❐ | A systematic review of statin-induced muscle problems in clinical trials. | PubMed #26886523. ❐ | 2 | 33 | Taylor and Kerry | PainSci #52275. ❐ | 36 | Hypermobility spectrum disorders | bone-deforming condition called Paget’s disease | 11 | ScienceBasedMedicine.org | 22 | PubMed #28051109. ❐ | 1 | 18 | PainSci #55028. ❐ | PubMed #27004164. ❐ | BOOKS | Neuroinflammation and Central Sensitization in Chronic and Widespread Pain. | THEORY | central sensitization | 43 | Drug related: | PainSci #52757. ❐ | Lymphoma | systems perspective on pain | Vitamin D Deficiency — Is There Really a Pandemic? | PubMed #30223011. ❐ | PubMed #11780656. ❐ | more detailed commentary on this paper. | unnecessary inflammation | Trigger points | Chronic pain in hypermobility syndrome and Ehlers-Danlos syndrome (hypermobility type): it is a challenge. | frozen shoulder | PubMed #21692974. ❐ | 29 | PubMed #20688875. ❐ | some object to it | 34 | in a letter to the journal | It's All in Your Head: True Stories of Imaginary Illness. | Benzodiazepene withdrawal (both erratic and chronic) | Mitochondrial reticulum for cellular energy distribution in muscle. | Stein | Statin-Associated Autoimmune Myopathy. | 19 | The cost of pain in Australia. | 5 | Ehlers–Danlos syndrome and the hypermobility spectrum disorders | The role of muscle biopsy in investigating isolated muscle pain. | donation page | fibromyalgia | 10 | neck cricks | Sezer | Muscle spasm, tension, contracture | PS Chronic, Subtle, Systemic Inflammation | Pain is Weird: Pain science reveals a volatile, misleading sensation that is often more than just a symptom, and sometimes worse than whatever started it | Opioid-induced hyperalgesia | 38 | ultimate | morning back pain | 17 | 8 | PubMed #29462012. ❐ | Chronic immune activation after infection | A genetic defect that exaggerates all sensation | PubMed #28850365. ❐ | PS Pain & Injury Survival Tips | 24 | Voltaren® | 4 | Brain glial activation in fibromyalgia - A multi-site positron emission tomography investigation. | mitochondrial disease, | PubMed #28476288. ❐ | icing | full bio and qualifications | neuroinflammation | PubMed #25464233. ❐ | Effects of Statins on Skeletal Muscle: A Perspective for Physical Therapists. | Entrapment of middle cluneal nerves as an unknown cause of low back pain. | Mammen | PubMed #22426836. ❐ | 778-968-0930&ensp | Genome-wide association study of multisite chronic pain in UK Biobank. | possible that “deep tissue” massage is also causing a lot of rhabdo | Writerly | 6 | Mitochondrial disease | 41 | 28 | 16 | neuro-inflammation | 40 | MS hug | When Chronic Pain Is Not "Chronic Pain": Lessons From 3 Decades of Pain. | THERAPY | Pain with literally no specific cause | Chronic, Subtle, Systemic Inflammation | 21 | Analysis of vitamin D levels in patients with and without statin-associated myalgia - a systematic review and meta-analysis of 7 studies with 2420 patients. | 42 | osteomalacia symptoms | Myelopathy (spinal cord impingement, especially and probably intermittent) | PainSci #55265. ❐ | PubMed #27959647. ❐ | PainSci #53097. ❐ | PainSci #52325. ❐ | Intravascular danger signals guide neutrophils to sites of sterile inflammation. | Vitamin D for Pain | DONATE | 23 | supplement

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